Occult HBV infection

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The clinical significance of occult HBV infection

The presence of hepatitis B virus (HBV) DNA in HBV surface antigen (HBsAg)-negative individuals is defined as occult HBV infection (OBI). OBI is related in some cases to infection with variant viruses (S-escape mutants) undetectable by HBsAg commercial kits. More frequently, however, it is due to infection with wild-type viruses that are strongly suppressed in their replication activity. OBI ma...

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occult hbv infection in rafsanjanese blood donors

objective: occult hepatitis b infection is a form of hepatitis in which despite of absence of detectable hbsag, hbv-dna is present in peripheral blood of patients. this clinical form of b hepatitis creates some problems for the iranian blood transfusion services. therefore, the aim of this study was the evaluation of status of occult hepatitis b infection in the rafsanjanese blood donors. mate...

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Occult HBV infection among a cohort of Nigerian adults.

OBJECTIVE To determine markers of HBV infection and detect the presence of its occult infection in serum of a cohort of adult Nigerians. METHODOLOGY The study involved 28 adult Nigerians with viral hepatitis (Group 1) and 28 apparently healthy adult Nigerians as controls (Group 2). Their sera were assayed for HBsAg, HBeAg, anti-HBe, anti-HBc, anti-HBs, and anti-HCV, while HBV DNA was determin...

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Occult HBV Infection: A Faceless Enemy in Liver Cancer Development

The hepatitis B virus (HBV) represents a worldwide public health problem; the virus is present in one third of the global population. However, this rate may in fact be higher due to occult hepatitis B virus infection (OBI). This condition is characterized by the presence of the viral genome in the liver of individuals sero-negative for the virus surface antigen (HBsAg). The causes of the absenc...

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Isolated Anti-HBc and Occult HBV Infection in Dialysis Patients

BACKGROUND Occult Hepatitis B virus (HBV) infection (OBI) is defined as the presence of HBV-DNA in the liver or serum with undetectable hepatitis B surface antigen (HBsAg). Hemodialysis (HD) patients are at risk of acquiring parenterally transmitted infections. OBJECTIVES The aim of this study was to assess the prevalence of OBI in HD patients. PATIENTS AND METHODS A hundred HBsAg negative ...

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ژورنال

عنوان ژورنال: Microbiologia Medica

سال: 2010

ISSN: 2280-6423

DOI: 10.4081/mm.2010.2436